RESEARCH
If you are passionate about integrating structural biology, AI, and biophysical chemistry to drive innovation in oncology‑driven precision medicine and translational research, you have come to the right place.
1. Biological and Biophysical Chemistry
Research Focus: Therapeutic Protein Target Prioritization & Tractability Validation
Dr. Erdogan’s lab designs and applies machine‑learning algorithms to analyze chemoproteomics datasets and identify novel druggable sites across proteomes of various organisms, including humans. These efforts address challenging diseases ranging from cancer to neurological disorders.
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Projects integrate chemical and structural biology techniques to empirically validate computational predictions, enabling the discovery of novel therapeutic drug‑targeting modalities.
Research Techniques
- Chemical proteomics
- Protein chemistry
- Organic and medicinal chemistry
- Machine learning and data science
2. Structural and Computational Biology
Research Focus: Structure–Function Relationships of Disease‑Linked Protein Variants
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Dr. Erdogan’s team investigates disease‑associated mutations and evaluates their effects on protein structure and function using a broad range of biochemical and biophysical methodologies.
Research Techniques
- Recombinant protein production
- X‑ray crystallography
- Bioinformatics and structural modeling
- Biochemical and biophysical assays.
